Apr 01, 2016 Molecular Cell Biology (8th edition) PDF, By Harvey Lodish and Arnold Berk, ISBN:, In writing the eighth edition of Molecular Cell Biology, we.
ExcerptModern biology is rooted in an understanding of the molecules within cells and of theinteractions between cells that allow construction of multicellular organisms. Themore we learn about the structure, function, and of different organisms,the more we recognize that all life processes exhibit remarkablesimilarities. Molecular Cell Biology concentrates on themacromolecules and reactions studied by biochemists, the processes described by cellbiologists, and the pathways identified by molecular biologists andgeneticists. In this millennium, two gathering forces will reshape molecular cellbiology:, the complete sequence of many organisms, and proteomics, aknowledge of all the possible shapes and functions that proteins employ.All the concepts of molecular cell biology continue to be derived from experiments,and powerful experimental tools that allow the study of living cells and organismsat higher and higher levels of are being developed constantly.
In thisfourth edition, we address the current state of molecular cell biology and lookforward to what further exploration will uncover in the twenty-first century. About the Authors. Preface. Acknowledgments. Supplements. 1.
The Dynamic Cell. 1.1. Evolution: At the Core of Molecular Change.
1.2. The Molecules of Life. 1.3. The Architecture of Cells. Cells Are Surrounded by Water-Impermeable Membranes.
Membranes Serve Functions Other Than Segregation. Prokaryotes Comprise a Single Membrane-Limited Compartment. Eukaryotic Cells Contain Many Organelles and a Complex Cytoskeleton.
Cellular DNA Is Packaged within Chromosomes. 1.4. The Life Cycle of Cells. The Cell Cycle Follows a Regular Timing Mechanism. Mitosis Apportions the Duplicated Chromosomes Equally to Daughter Cells. Cell Differentiation Creates New Types of Cells.
Cells Die by Suicide. 1.5. Cells into Tissues. Multicellularity Requires Extracellular Glues. Tissues Are Organized into Organs. Body Plan and Rudimentary Tissues Form Early in Embryonic Development.
1.6. Molecular Cell Biology: An Integrated View of Cells at Work. 2. Chemical Foundations.
2.1. Covalent Bonds. Each Atom Can Make a Defined Number of Covalent Bonds. The Making or Breaking of Covalent Bonds Involves Large Energy Changes. Covalent Bonds Have Characteristic Geometries.
Electrons Are Shared Unequally in Polar Covalent Bonds. Asymmetric Carbon Atoms Are Present in Most Biological Molecules. α and β Glycosidic Bonds Link Monosaccharides. SUMMARY.
2.2. Noncovalent Bonds.
The Hydrogen Bond Underlies Water’s Chemical and Biological Properties. Ionic Interactions Are Attractions between Oppositely Charged Ions. Van der Waals Interactions Are Caused by Transient Dipoles. Hydrophobic Bonds Cause Nonpolar Molecules to Adhere to One Another. Multiple Noncovalent Bonds Can Confer Binding Specificity.
Phospholipids Are Amphipathic Molecules. The Phospholipid Bilayer Forms the Basic Structure of All Biomembranes. SUMMARY. 2.3.
Chemical Equilibrium. Equilibrium Constants Reflect the Extent of a Chemical Reaction. The Concentration of Complexes Can Be Estimated from Equilibrium Constants for Binding Reactions. Biological Fluids Have Characteristic pH Values. Hydrogen Ions Are Released by Acids and Taken Up by Bases. The Henderson-Hasselbalch Equation Relates pH and K eq of anAcid-Base System.
Buffers Maintain the pH of Intracellular and Extracellular Fluids. SUMMARY. 2.4.
'The value of this incredibly extensive reference book lies in the attention it gives to explaining methods and techniques as fullly as is possible in a text that addresses so many aspects of this fast-expanding field.' Chris Clegg, Journal of Biological Education 'Molecular Cell Biology literally does what it says on the tin: it provides a fantastic overview of much of the material studied in any molecular biology-based degree, and is thoroughly recommended.'
- Emma Prior, Times Higher Educational Supplement Read more.
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